Title
Individual therapy for the treatment of arterial hypertension
Poster
Description
Maria Garalova
Medical Faculty, Medical University of Sofia
Subject
Arterial hypertension affects about 25% of the working population of developed countries. It is known as the "silent killer" because it has been going on for a long time without manifest symptoms, but it leads to serious illnesses and complications. Antihypertensive drugs affect different pathogenetic mechanisms. The major classes of anti-hypertensive drugs are: medicines that affect the renin-angiotensin-aldosterone system (angiotensin converting enzyme inhibitors, angiotensin-1 receptor blockers, direct renin inhibitors), drugs that reduce elevated sympathetic tonic - beta blockers, calcium antagonisms. Each drug group has its own possitive and negative sides. They have known and unknown side effects and interactions. Patient therapy must be consistent with the risk factors, concomitant illness, mental and general physical condition of the person. If possible, genetic analysis should also be made when there is a family history of this disease.
Sometimes therapy can be detrimental to the patient when not individually determined. Hypertension is a condition of sustained elevated blood pressure. Arterial hypertension in people over 18 years of age is considered to be established at a systolic blood pressure ≥ 140 mmHg and/or a diastolic blood pressure ≥ 90 mmHg as the mean of repeated measurements with at least three consecutive medical checkups at different times. It is unacceptable to start antihypertensive therapy without a diagnosis. The treatment of arterial hypertension requires a change of lifestyle, physical activity, denial of harmful habits, and proper drug therapy. Medicines are selected on the basis of a complex evaluation and benefit/risk ratio.
Sometimes therapy can be detrimental to the patient when not individually determined. Hypertension is a condition of sustained elevated blood pressure. Arterial hypertension in people over 18 years of age is considered to be established at a systolic blood pressure ≥ 140 mmHg and/or a diastolic blood pressure ≥ 90 mmHg as the mean of repeated measurements with at least three consecutive medical checkups at different times. It is unacceptable to start antihypertensive therapy without a diagnosis. The treatment of arterial hypertension requires a change of lifestyle, physical activity, denial of harmful habits, and proper drug therapy. Medicines are selected on the basis of a complex evaluation and benefit/risk ratio.