Contemporary Approaches to Diagnosing and Treating Disease of Alzheimer

Contemporary Approaches to Diagnosing and Treating Disease of Alzheimer

Poster

Stefka Stoianova, Tsvetomir Deliiski, Kalina Andreevska
Faculty of Chemistry and Pharmacy, Sofia University "St. Kliment Ohridski ", Bulgaria

Introduction: Alzheimer's disease is ranked sixth worldwide in mortality. This is a multifactorial neurodegenerative disease with a progressive course, which is considered as the 21st century epidemic. According to statistical data, the number of people affected is expected to triple by 2050 year (around 54 million people in globally). Dementia studies have been extremely important in recent years because increase in people's longevity. Undoubtedly, there is the great socio-economic and medical significance of diagnostics, treatment and care of the sick of dementia in our country as a rapidly aging nation. Aim: To explore modern approaches to diagnosis and treatment of Alzheimer's disease. Methods and Materials: We used a documentary method based on the National Consensus on early diagnosis and treatment of Alzheimer's disease and data of World Report Alzheimer 2018 of Alzheimer Disease International (ADI). Results and discussion: Besides the classic choice of treatment - acetylcholinesterase inhibitors, begins to use of atypical Alzheimer's disease drugs such as statins, estrogens, NSAIDs; there are attempts at development of monoclonal antibodies that would successfully affect the disease. In the course of the disease, patients have a number of additional symptoms such as aggression and psychomotor agitation, which further compromise treatment and are the cause of non-compliance. To overcome this, begins the development and introduction of new medical forms such as transdermal plasters. Conclusion: The extreme medical - social significance of this devastating human intellect condition is a result of both - the high morbidity and progressive loss of patient autonomy and the specific care required for extraordinary health, moral, financial expenditures and access to modern therapy.
Key words: Alzheimer, treatment approaches, diagnostic