Prunella vulgaris herbal products: an analytical overview

Prunella vulgaris herbal products: an analytical overview

Poster

Venelina Angelkova1, Ivan Svinyarov1, Anely Nedelcheva1;
1Faculty of Chemistry and Pharmacy, Sofia University "St. Kliment Ohridski", Sofia

The focus of this study is the products containing herbal substances and/or herbal preparations of common selfheal, established from publicly available databases. The herbal products have been analyzed to determine their diversity, structure, active substances, functions, target area and application. A comparative analysis was carried out according to the known data on the biological activity of Prunella vulgaris L. and the herbal substances Prunellae herba and Prunellae spica. Over 50 herbal products have been identified: dietary supplements (52%) and cosmetics (41%). Both mono-components of Prunellae herba and combinations with plants mainly from traditional Chinese medicine, but also species present in the Bulgarian flora are widely used. Nine cosmetic ingredients have been registered with skin and hair conditioning and protecting functions, antioxidant function, as well as an emollient and antiseborrhoeic (CosIng,2022). Fermented filtrates and hydrolyzed extracts are present. Compared to registered, established cosmetics have a wider range of functions based on traditional knowledge. The main purpose of the dietary supplements is as immunostimulants and in the treatment of skin diseases and superficial wounds. Prunella vulgaris is a pharmacopoeial medicinal plant (Common selfheal fruit-spike, Ph. Eur. 10.0, 2439:01/2017). No registered herbal medicinal products have been identified (BDA,2022). The analysis shows Prunella vulgaris as a herb with potential for the development of herbal medicinal products.
The authors are grateful to the financial support of Bulgarian NSF at the Ministry of Education and Science, Contract 2901/KP-06-China/15/2020.
Keywords: Common selfheal, medicinal products, traditional knowledge